Interferon – a part of the immune system
The role of interferons in the evolution of vertebratesInterferons (IFN) are the basis of antiviral protection in all vertebrates. When attacked by viral particles, almost any cell in the body can synthesize interferon molecules, informing the rest of the cells that it is infected. Immune cells move towards this signal to eliminate the danger faster. Tissue cells, having received the IFN signal, rearrange their biochemical processes to protect themselves from viruses or slow down their reproduction if they failed to protect themselves. Innate immunity is a quick but crude response to danger. The innate immune system triggers the acquired immune system through the interferon system – an exact but slow tool for protecting the body from external influences. The IFN molecule does not fight directly against the viral particle but triggers all the antiviral protection mechanisms without exception. [Read more…] |
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Actual knowledge about human interferonInterferon in the human body is produced and functions based on the same principles as in other vertebrates. The human IFN system’s peculiarity is the variety of protective and regulatory processes triggered or stimulated by interferon. Depending on which genes encode the form of the IFN molecule, there are 3 types of interferon. People have been using interferon since 1960 for the prevention and treatment of viral, fungal, and oncological diseases. [Read more…] n 2020, the study of human interferon was mainly aimed at combating the COVID-19 pandemic. Some current topics: |
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Interferon Prevents Coronavirus Cytokine Storm in Diabetic Patients
Interferon increases levels of the enzyme SETDB2, which suppresses inflammation
Interferon Autoantibodies Increase The Risk of Critical COVID-19 in Elders
Autoantibodies that neutralize type I interferons are present in 4% of uninfected people over 70 and are responsible for 20% of deaths from COVID-19
Interferon-α2b inhalation improves clinical outcomes in COVID-19 patients
The timing of treatment initiation is crucial – up to 5 days from the onset of symptoms