Diseases
Type I Interferon Responses Enhance the Regenerative Activity of Salivary Gland Stem Cells After Radiotherapy
Blockade of IFN-β or RIG-I Attenuates This Effect
Antiviral Defense of the Nasal Mucosa Weakens With Age
Prolonged Infection Leads to More Severe Disease
Endogenous Retroelements as Regulators of Oral Tolerance
The cGAS–STING Pathway Is Required for Protection Against Food Allergy
Therapeutic Potential of Type I Interferon in Enhancing Sensitivity to Cancer Immunotherapy
Type I Interferon Regulates Metastasis and Improves Tumor Response to Immune Checkpoint Blockade
Long COVID: Chronic Inflammation and T Cell Dysfunction
JAK–STAT, IL-6, and Interferon Signaling Pathways as Potential Therapeutic Targets
Nasal Interferon Reduces the Period of Infectiousness in Children Infected With Coronavirus
Shortening the Period – Containing the Pandemic
Gut Microbiota as a Regulator of Innate Antiviral Immunity
Intestinal Bacteria Are Required for Basal Activation of the cGAS–STING–IFN-I Axis
Children With Severe Influenza Produce Little Interferon in the Nose
Mild Influenza Is Associated With Much Higher Interferon Levels
Autoantibodies to Interferon Alpha in Patients With Antibody Deficiency
Autoantibodies Are Rare and Do Not Affect Coronavirus Vaccination
Breastfeeding Protects Infants From Severe Influenza by Activating Type I Interferon Production
The Effect Is Observed for Influenza but Not for RSV or Metapneumovirus
Autoantibodies to Type I Interferons Increase the Risk of Fulminant Hepatitis Caused by HSV
Therapeutic Opportunities With Interferons
Autoantibodies to Type I Interferons – A Risk Factor for Fatal Avian Influenza H5N1
A Case of Pneumonia in a 71-Year-Old Man
Early RSV Infection and Familial Allergy Increase the Risk of Asthma
RSV Immunoprophylaxis Prevents Allergic Airway Inflammation in Mice
Vaccine Targeting IgE
IgE-K Induces Neutralizing Antibodies Similar to Omalizumab
Development of a Universal Influenza A Vaccine
Antigen AC–Anhui Provides Broad Immune Protection
PLD4 Mutations as a Genetic Cause of Systemic Lupus Erythematosus
PLD4 Deficiency Leads to Excessive Activation of the Type I Interferon Pathway
Nasal Interferon Restores the Nasal Immune Landscape During Viral Infection
Type I Interferon Accelerates Clearance of Metapneumovirus
Infections as a Key Factor in Prematurity and Infant Mortality
The Importance of Preventing ARVI and STIs in Reducing the Risk of Placental Pathology
Prevention of ARVI in Pregnant Women and Newborns: Evaluating the Efficacy and Safety of Intranasal Interferon
Intranasal Interferon α-2b Prevents ARVI and Mitigates Disease Severity
Type I Interferons Are Essential for Early Control of Candida albicans in Vulvovaginal Candidiasis
Absence of IFN-I Signaling Increases Fungal Burden and Inflammation
How the Immune System Responds to Tuberculosis: The Role of Type I Interferons, Neutrophils and T Cells
Early Immune Mechanisms That Determine the Outcome of Mycobacterium Tuberculosis Infection
Seven Puzzles of Coronavirus
Pneumonia, MIS-C, Neuro-COVID, COVID Toes, Post-COVID Syndrome, Resistance to Infection, and Adverse Reactions to mRNA Vaccines
Pregnancy and Breastfeeding Protect Against Breast Cancer
CD8+ T Cells Provide Antitumor Protection
Defects in the Type I Interferon Pathway Contribute to Immunopathology in Herpetic Encephalitis
NF-κB Blockade Reduces the Severity of Herpetic Encephalitis in Mice with the IRF3 R278Q Mutation
Ketogenic Diet During Cancer Immunotherapy Boosts Interferon Production
Survival Increases from 42% to 67%
High-Dose Influenza Vaccine Reduces Risk of Cardiovascular Complications in Older Adults
Hospitalization Risk for Heart Failure Decreases by Nearly 20%
Itaconate Protects Against Inflammation in Atherosclerosis
Itaconate Reduces ROS Formation, Type I Interferon Production, and IL-1β Secretion
Physical Exercise After Colorectal Cancer Treatment Reduces Recurrence Risk by 28%
Possible Mechanism – Reduced Inflammation and Enhanced Immune Surveillance
Fumarate Enhances Interferon Production During Viral Infection
Fumarate Directly Activates MAVS – A Central Component of the Antiviral Signaling Pathway
Type I and Type III Interferons Disrupt Lung Repair After Viral Infection
Interferon-λ Impairs Lung Barrier Function via p53 Activation
mRNA IFN-I Nanoparticles Suppress Lung Metastases
A Candidate for Third-Generation Interferon-Based Cancer Therapy
NKp30 NK Cells Determine the Effectiveness of Peg-IFN-α2b Therapy in Chronic Hepatitis B
Why Interferon Therapy Is Not Effective for Everyone
How Aging Alters the Response to Coronavirus
STAT3-Dependent Processes – The Basis of Severe COVID-19 in the Elderly
Interferon-α Promotes Functional Cure of Chronic Hepatitis B by Inducing Liver Steatosis
Elevated Lipid Levels May Improve Response to Peg-IFN Therapy
SLIC-IFN-γ: Bacteria That Help Overcome Resistance to Cancer Immunotherapy
Targeted Delivery of Interferon-γ Enhances the Effect of PD-1 Blockade
Influenza and COVID-19 – Potential Triggers of Cancer Progression
Respiratory Viruses Elevate IL-6 Levels, Activating Dormant Breast Cancer Cells
Regulatory T Cells in Brown Adipose Tissue Support Thermogenesis by Suppressing Interferon-Gamma Production
Treg Protects Mitochondria and Prevents Metabolic Dysfunction
Interferon Gamma Reduces the Angiogenic Potential of Cancer Cells
IFN-γ Suppresses Perlecan Gene Expression and Tumor Growth
CD388 – A New Drug for the Treatment and Prevention of Influenza
The Drug Blocks Neuraminidase and Protects Against a Broad Range of Influenza A and B Viruses
SPENCD: A Rare Bone Disease Identified as an Interferonopathy
ACP5 Gene Mutations Lead to Excessive Interferon Pathway Activation
Type I Interferons Increase Gonococcal Survival
Interferon-Epsilon Promotes Gonorrhea Progression
Type I Interferons and T Cell Dysregulation in IBD
Endogenous IFN-β Controls Intestinal Inflammation
Interferons in Inflammatory Bowel Disease
The Protective and Damaging Roles of Interferons and Their Therapeutic Potential
Interferon-γ and Serotonin in Irritable Bowel Syndrome
Interferon-γ Increases Serotonin Availability, Disrupting Gut Motility
Why Bats Carry Viruses Without Getting Sick
Interferon Lambda Suppresses Marburg Virus
Type I Interferon Reduces Monkeypox Severity
Early Administration Maximizes Antiviral Effectiveness
Interferon-Gamma Against Leptomeningeal Metastases
For Antitumor Effect, IFNγ Requires NK Cells
Next-Generation Cancer and Virus Vaccines: The SABER Platform
SABER molecules enhance cross-presentation by improving antigen delivery to the endoplasmic reticulum
Β-Glucan Reprograms Immunity and Reduces Influenza Severity
Protective effect depends on type I interferon, Dectin-1, and T cells
PD-L1 Suppresses Interferon Response, Enhancing Oncolytic Virus Efficacy”
Combining oncolytic viruses with PD-1/PD-L1 blockers is a promising cancer treatment strategy
How to Protect a Newborn: Vaccination Before and After Birth
Antibody Transfer Before and After Delivery
Interferon-gamma suppresses the anti-tumor activity of T cells
Ablation of IFN-γ receptor on CD8+ T cells enhances tumor control
METTL3 Inhibitor Triggers Interferon Response, Enhancing Anti-Tumor Immunity
A combination of METTL3 inhibitor and anti-PD-1 improves cancer survival
Shingles vaccination reduces dementia risk by 20%
A natural experiment among residents of Wales
Influenza During Pregnancy Disrupts Embryonic Brain Development
Severity of Pathology Depends on Viral Load
Type I Interferons Produced During Viral Infections Suppress Metastasis
RSV Infection Prevents Lung Metastasis Development
Type I Interferons Suppress Malaria at the Liver Stage
Two Mechanisms of Plasmodium Suppression in the Liver
IL-27 Enhances Anti-Tumor T Cell Response
IL-27 Improves Cancer Treatment Effectiveness
Aspirin Prevents Metastasis
Aspirin inhibits TXA2 activity, enhancing T-cell activation
Type I Interferons Help NK Cells Absorb Iron
Iron Enhances the Antiviral Activity of NK Cells
Tonsils as a Potential Reservoir for Coronavirus
SARS-CoV-2 Penetrates Tonsils and Suppresses Immune Response
Tonsil Removal Reduces the Risk of COVID-19
Study on Over 500,000 Individuals
How Nasopharyngeal Lymphoid Tissue Responds to SARS-CoV-2 in Adults
Lymphoid Tissue Provides Coordinated Defense Against Viruses
Rapid Decline of Interferon-α2 is Associated with the Risk of Death from COVID-19
Type I Interferon Treatment May Help Severe Patients
Type I and III Interferons in Asthma and Exacerbations
Respiratory Infections Trigger Asthma Exacerbations
Reactivating HIV to Eradicate It
Combination Therapy for HIV: Panobinostat and Pegylated Interferon-α2a
Naïve Antibodies Provide Protection Against H5Nx Influenza
Naïve B Cells Recognize Hemagglutinin of Avian Influenza
Protection Against Influenza: The Critical Role of Interferon-Lambda
Interferon-λ Signaling in Macrophages is Essential for Antiviral Response to Influenza
NDV-GT – a virus that treats cancer
The oncolytic virus induces a hyperacute rejection response
Rotavirus NSP1 Protein Suppresses Type I and III Interferon Production
NSP1 Enables Rotavirus to Evade Immune Detection
Increased Frequency of Dendritic Cells Following Antiretroviral Therapy Interruption Indicates Subclinical HIV Replication
Dendritic Cells Lose Their Ability to Produce Interferon-α
Early Interferon Response Protects Against Coronavirus Infection Despite Exposure
Increased IFN-Related Gene Activity Within 6 Hours After Exposure Prevents Infection
Diagnosing ARVI via Interferon Levels
Nasal Interferon Levels Combined with PCR Testing Improve Diagnostic Accuracy to 94%
Lurbinectedin and Atezolizumab for Small-Cell Lung Cancer
Lurbinectedin Enhances IFN Signaling to Boost Immunotherapy Efficacy
New Frontiers in Lung Cancer Treatment: STAT3 and Interferon Therapy
The STAT3-STING-IFN Axis Governs Small-Cell Lung Cancer Metastasis
Persistence of SARS-CoV-2 in Alveolar Macrophages is Regulated by IFN-γ and NK Cells
SARS-CoV-2 Exploits MHC-E to Evade the Immune Response
Vulvovaginal Candidiasis: Causes, Pathogenesis, Treatment
How the Body Interacts with Fungus in Acute and Recurrent Vulvovaginal Candidiasis
Recombinant Shingles Vaccine Reduces Dementia Risk
17% Greater Effectiveness Compared to Live Vaccine
Vaccines Developed in the Early 2000s May Protect Against New H5N1 Influenza
MF59 and AS03 Adjuvanted Vaccines Induce Cross-Neutralizing Antibodies
Iron Deficiency Suppresses Memory T-Cell Response to Influenza
Iron Deficiency Reduces Interferon-Gamma Production and Weakens Antiviral Defense
Magnesium for Migraine: Mechanisms, Forms, and Efficacy
Magnesium in Neurophysiological Processes
Interstitial Macrophages: Key Culprits in Severe COVID-19
The Coronavirus Exploits Interstitial Macrophages for Replication
Iron Restriction Blocks Viral Replication
However, iron is necessary for the immune response
COVID-19 Enhances Flu Response by Creating Innate Immune Memory
Coronavirus alters the genetic activity of alveolar macrophages
Different Neurons Control Sneezing and Coughing
Suppressing MrgprC11 Neurons – A New Approach to Treating Allergies and Respiratory Infections
Impaired Tolerance of Self-Tissues Leads to Autoantibodies Against IFN-I
Autoantibodies against type I interferons (IFN-I) increase susceptibility to severe infections
Why Adequate Magnesium and Vitamin D Balance is Essential
The Critical Role of Magnesium in Vitamin D Bioavailability and Biological Activity
Микроглия и рассеянный склероз: ключ к новым методам лечения
Недавно выявленные подтипы микроглии, и как они влияют на развитие РС
Cardiomyocytes: Unexpected Players in Myocardial Infarction Pathogenesis
Type I Interferon Produced by Cardiomyocytes Increases the Risk of Cardiac Wall Rupture
Tumor Microbiome: How Bacteria Influence Cancer Development
Bacteria Can Increase Cancer Aggressiveness
How Obesity Worsens the Course of Multiple Sclerosis in Women
Interferon-α: A Key Factor in the Development of Autoimmune Diseases in Obesity
The Cause of Fatigue in Post-COVID Syndrome: Tryptophan Catabolites, Inflammation, and Insulin Resistance
Early Control of Inflammation Can Reduce the Risk of Severe Post-COVID Syndrome
Predicting the Success of COVID-19 Treatment with Dexamethasone Based on Monocyte Gene Activity
Dexamethasone: Not Just an Immunosuppressant but Also an Immunomodulator
Interferon-γ Contributes to Respiratory Complications After COVID-19
Blocking IFN-γ: A New Approach to Treating Post-COVID Syndrome
How the Body Responds to Coronavirus at Different Stages of Infection
Scientists Infect Volunteers with SARS-CoV-2 to Understand the Immune System's Battle Against the Virus
Pharmacodynamics of Nasal Interferon Alpha-2b and Effective Prevention of Coronavirus Infection
Research on high-risk groups
Iron Supplementation Linked to Chronic Kidney Disease in Hypertension Patients
Iron and Antihypertensive Medications: A Dangerous Combination